Abbr.	Onset	Proteine	Source on NCBI	               Isoforms	linked with / remarks	Locus	
CLN1	infancy, or any age up to adulthood	PPT1
palmitoyl-protein-thioesterase 1	http://www.ncbi.nlm.nih.gov/gene/5538?ordinalpos=5&itool=EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVDocSum	NP_000301                306 aa 
Isoform1	NP_001136076             203 aa        
Isoform2	CLN4	1p32	
CLN2	late infancy, or at later ages	TPP1
tripeptidyl-peptidase I preproprotein
	http://www.ncbi.nlm.nih.gov/gene/1200?ordinalpos=5&itool=EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVDocSum	NP_000382                563 aa 
		CLN1
http://www.ncbi.nlm.nih.gov/pubmed/16518810	11p15	
CLN3	juvenile
	??
lysosomal function ??	http://www.ncbi.nlm.nih.gov/gene/1201?ordinalpos=2&itool=EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVDocSum

CLN3 interacts with Notch and Jun N-terminal 
kinase signalling pathways.
	NP_001035897             438 aa
Variant 1 (longer 
transcript)
	NP_000077                438 aa
Variant 2	Variant 2 differs in the 5' UTR compared to variant 1. Both variants 1 and 2  encode the same protein.
	16p12.1	
CLN4	adult
(Kufs disease)	no, phenotype only	http://www.ncbi.nlm.nih.gov/gene/1202?ordinalpos=1&itool=EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVDocSum	
			??	
CLN5	late infancy, or at later ages	??	http://www.ncbi.nlm.nih.gov/gene/1203?ordinalpos=1&itool=EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVDocSum

http://www.ncbi.nlm.nih.gov/entrez/dispomim.
cgi?id=608102
	NP_006484                407 aa 
		CLN2, CLN3

Mol Biol Cell. 2002 Jul;13(7):2410-20	13q21.1-q32	
CLN6	late infancy	?? 	http://www.ncbi.nlm.nih.gov/protein/NP_060352.1?report=genpept	NP_060352                311 aa 		11p15 (CTSD; CLN1)
http://hmg.oxfordjournals.org/cgi/content/abstract/6/4/591	15q23	
CLN7/
MFSD8	late infancy	transporter protein, substrate(s) not known	http://www.ncbi.nlm.nih.gov/protein/NP_689991.1?report=genpept

http://en.wikipedia.org/wiki/Protein_disulfide_isomerase

http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1299221  (PDIs)
	NP_689991                518 aa            			4q28.2	
CLN8	late infancy
	??	http://www.ncbi.nlm.nih.gov/protein/NP_061764.2?report=genpept	NP_061764                286 aa 
		Northern epilepsy	8p23
	
CLN9	juvenile	??	http://www.ncbi.nlm.nih.gov/pubmed/15349861
	no defined			??	
CLN10/
CTSD	early childhood	cathepsin D	http://www.ncbi.nlm.nih.gov/protein/NP_001900.1?report=genpept
http://www.ncbi.nlm.nih.gov/gene/1509?ordinalpos=2&itool=EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVDocSum	NP_001900                412 aa
			11p15.5